Animal Welfare Act and Animal Welfare Regulations:

ARENA and OLAW IACUC Guidebook, 2nd Ed., 2002 

The AVMA Guidelines for the Euthanasia of Animals (2020)

Biosafety in Microbiological and Biomedical Laboratories (BMBL), 6th edition, U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institutes of Health

Code of Federal Regulations

FDA webpage on animals with intentional genomic alterations

Federal Register

Good Laboratory Practice for Nonclinical Laboratory Studies, Code of Federal Regulations, Title 21, Part 58

Guide for the Care and Use of Laboratory Animals - National Research Council - 2011 edition

Health Research Extension Act - PUBLIC LAW 99-158, November 20, 1985 "Animals in Research"

Memorandum of Understanding Concerning Laboratory Animal Welfare, among APHIS (USDA), the Food and Drug Administration, and the NIH

Monoclonal Antibody Production, A Report of the Committee on Methods of Producing Monoclonal Antibodies, Institute for Laboratory Animal Research, National Research Council, 1999, Guidance Document

National Institutes of Health, Office of Laboratory Animal Welfare

NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) - Relevant Regulations, Guidelines and Laws

Occupational Health and Safety in the Care and Use of Research Animals, National Academy of Sciences, 1997  

Office of Laboratory Animal Welfare (OLAW), National Institutes of Health:

Office of Management and Budget (OMB): Cost Principles for Educational Institutions - Circular No. A-21), relocated to 2 CFR, Part 220 (PDF)

Policy on Humane Care and Use of Laboratory Animals: with the Health Research Extension Act of 1985; Public Health Service / Office for Laboratory Animal Welfare (OLAW), Revised 2015

Recombinant DNA Molecules: NIH Guidelines for Research Involving Recombinant DNA Molecules, from the Office of Biotechnology Activities

U.S. Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research and Training


USDA: Agricultural Research Service (intramural), ARS * CSREES * ERS * NASS. Policies and Procedures: Animal Care and Use Committee Directive, 2002, (Directive 130.4)

Veterans Affairs, US Department of: Use of Animals in Research Documents and Resources