Monday, October 14
MORNING


WORKSHOPS

W-01A Microsurgery Skills Training Using Surgical Loupes (offered twice, also Monday 1:00 PM)
8:00 AM - 12:00 PM/Room: 301
Leader: Robert F Hoyt Jr
Faculty: Robert F Hoyt Jr, Randall R Clevenger, Timothy J Hunt, Karen Keeran, Tom Thomas, Tannia Clark, Elena Kuznetsova, Gayle Nugent, Victoria L Haley, Kenneth Jeffries, Tanya Herzog, Audrey Noguchi
Facilitator: TBN
Workshop Fee: $250 Workshop Limit: 20

Performing surgical procedures with the aid of magnification has gained widespread use in human medicine over the past 30 years. Using surgical loupes, surgeons can now routinely perform procedures on very small structures that were considered impossible only a few decades ago. Within the past 20 years, the use of magnification to perform microsurgical techniques has also quickly spread to other health care disciplines, including dentists and dermatologists, to increase surgical precision. Using them is now considered the standard of care. The importance of microsurgery to biomedical research has, unfortunately, only just begun to be realized. Because of their small body structures, laboratory animals, such as rats and mice, have generally not been considered as animal models for many types of surgical procedures routinely performed in biomedical research. Investigators have rather elected to use larger species such as dogs, pigs, sheep, rabbits, or nonhuman primates for such modeling because both surgical support equipment is more readily available, and the surgical techniques are more familiar to the support personnel. The recent shift to using genetically engineered rodents, especially mice, has now resulted in increased researcher desires to use these animals in more sophisticated modeling procedures, especially surgery. Rather than being limited to only simple procedures such as IM, IP, or IV injections, researchers using microsurgery can now perform complex surgical procedures on many rodent organ systems, such as the heart, lungs, and the gastrointestinal tract. Training will be conducted in 2 two phases: a) teaching students to develop technical skills by performing exercises using surgical loupes and b) applying these skills to perform simple surgical procedures using rodent and organ surrogates.

This Workshop is sponsored in part by Q-Optics, RICA Surgical Products, SurgiReal Products, Inc., and Supramid Suture.

W-02 Perioperative Anesthetic Monitoring

8:00 AM - 12:00 PM/Room: 302
Leader: Cholawat Pacharinsak
Faculty:
Facilitator: TBA
Workshop Fee: $150 Workshop Limit: 30

General anesthesia alters multiple physiologic responses of the body. Therefore, to have safe anesthesia, anesthetists should monitor patients starting from premedication to recovery. Monitoring requires anesthetists to have a thorough understanding of the various monitoring equipment used, including the interpretation of information generated. One big advantage of anesthetic monitoring is to alert anesthetists regarding arising complications so anesthetists can take the necessary actions to correct the complications before they become irreversible. This workshop will focus on basic laboratory animal monitoring methods, including ECG, blood pressure, ETCO2, %SpO2, and body temperature. This dry workshop is suited for veterinarians, veterinary technicians, IACUC members, and scientists.

This Workshop is sponsored in part by Kent Scientific.

W-03 Successful Operation of a Gnotobiotics Facility

8:00 AM - 12:00 PM/Room: 304
Leaders: Alton G Swennes and Betty R Theriault
Faculty: Stephanie W Fowler, Joshua M Frost, Allison R Rogala, Alton G Swennes, Betty R Theriault
Facilitator: Julia R Krout
Workshop Fee: $150 Workshop Limit: 50

This workshop is designed to provide guidance to those in the early stages of developing a gnotobiotics program. The workshop will provide background on facility design and requirements, sterilization techniques and their limitations, and the effective use of common equipment. Discussion will focus on the use of flexible film isolators (sterilization, cylinder packing, and port entry) and positive-pressure sealed IVC systems, including key procedural aspects that enable the maintenance of germ-free or gnotobiotic animals. Participants will gain perspective from workshop faculty that have developed large academically oriented programs. This workshop targets those that are currently or might become involved in setting up a gnotobiotics program, including managers, veterinarians, research scientists, and program administrators. Attendees will be introduced to the variety of equipment options available and the current standards in the field of gnotobiology. Participants will leave the workshop with a basic understanding of the central concepts required to operate a gnotobiotics program, including both facility management and basic technical competencies. This will provide a foundation to those that are new to the field.

This Workshop is sponsored in part by Tecniplast, Allentown, Class Biologically Clean, Taconic, and Charles River.

W-04 What Generational Gap? Effectively Working and Leading across Generational Culture Differences

8:00 AM - 12:00 PM/Room: 303
Leader/Faculty: Jamie Mueller
Facilitator: TBN
Workshop Fee: $150 Workshop Limit: 50

The topic of working across generations is not a new one. However, as potentially five generations will be working side by side by 2020, the question still remains of how to work and lead effectively across generational differences. In addition, the question of how to address the differences, perceived or real, also requires new thinking. To what degree is knowledge of the other generations helpful or hurtful in giving those working across generations the support, skills and wisdom they need to do the hard work of managing and leading with difference at work? This workshop will address these questions as well as consider the balance of (a) knowledge of one's own generation, (b) the other generations and, (c) skills in dealing with and responding to difference. Participants will increase their overall awareness and understanding of difference across generations as well as learn strategies to communicate and manage conflict in culturally diverse environments. This workshop is targeted to leaders, directors, and managers who manage team members from different generations and cultures, as well as team members who work and collaborate with different generations and cultures.


SEMINARS

A Practical Guide to Change Management in the Laboratory Animal Science Environment
8:00 AM - 10:15 AM/Room: Mile High Ballroom 1A
Leader/Moderator: Lois A Zitzow
Facilitator: TBN

Change in any organization is inevitable, and programs involved in laboratory animal science are no exception. Advances in technology, improvements in veterinary care, operational efficiency or stressors, and modifications in regulatory guidelines, coupled with scientific progress and institutional change, can create significant alterations in how a laboratory animal program operates. These changes can have a substantial impact, both positive and negative, on employee culture and productivity. The goal of the seminar is to give participants the tools needed to successfully manage change. Participants in this seminar will learn about some key models of organizational change and the impact of change on employees. Providing participants with different approaches and tools used from real-life examples will be central to the seminar. If you are looking to improve your workplace and implement successful change while minimizing stress on your coworkers, this seminar is for you. The target audience is individuals at all organizational levels, including directors, managers, supervisors, and team leaders.

Speakers/Topics:

8:00Lois A ZitzowWelcome and Introductions
8:05Lesley A ColbyThe Psychology of Change and How People React to It
8:25Lois A ZitzowSet the Stage, Decide What to Do, Make it Happen, and Make It Stick: The Kotter Method
8:50Christopher L MedinaMoving the Elephant: Heath’s Method
9:15Ann M SchiavettaPutting It All Together
9:40All PresentersDiscussion with Case Scenarios

Changing Times in the Animal Research Oversight Environment
8:00 AM - 10:15 AM/Room: Mile High Ballroom 2A
Leader/Moderator: B Taylor Bennett
Facilitator: Rocco Praglowski

On December 7, 2018, the National Institutes of Health (NIH) released the Draft Report on Recommendations to Reduce Administrative Burden on Researchers in response to the mandate in Section 2034 of the 21st Century Cures Act (Cures). The draft report contained actions proposed by the working group from the NIH, USDA, and FDA to reduce administrative burden on investigators while maintaining the integrity and credibility of research findings and protection of research animals. In addition, the USDA has been reviewing the Animal Care Policy Manual and the Animal Welfare Inspection Guide. The changes that will occur as result of these activities will have an impact how animal care and use programs are managed. This seminar will provide the attendees with an opportunity to hear from representatives of the USDA, OLAW, AAALAC, and NABR regarding possible changes, as well as other ongoing issues, within their organization and to discuss with those representatives how their organization’s activities impact the environment in which we work and what changes to expect in the future. Questions for the panelists can be submitted to btbdvm@yahoo.com. The target audience is those who need to keep current with the regulations and requirements for conducting animal based biomedical research.

Speakers/Topics:

8:00B Taylor BennettWelcome and Introductions
8:10B Taylor BennettDiscussion
8:55Robert GibbensUSDA Update
9:15Patricia A BrownOLAW Update
9:35Kathryn BayneAAALAC Update
9:55Matthew R BaileyNABR Update

This Seminar is sponsored in part by National Association for Biomedical Research (NABR), United States Department of Agriculture (USDA) APHIS Animal Care and National Institutes of Health (NIH), Office of Laboratory Animal Welfare (OLAW) and AAALAC International.

One Health: From Research to Application
8:00 AM - 10:15 AM/Room: Mile High Ballroom 4A
Leader/Moderator: Sue VandeWoude
Facilitator: Wendy R Williams

One Health is defined by the CDC as a collaborative, multisectoral, and transdisciplinary approach—working at the local, regional, national, and global levels—with the goal of achieving optimal health outcomes recognizing the interconnection between people, animals, plants, and their shared environment. We will highlight the laboratory and clinical research of human and veterinary investigators seeking to understand these relationships using translational medicine. We will discover how experts in veterinary and human medicine are using stem cell therapy and regenerative medicine to treat some of medicine’s toughest cases. These will include the use of genetically modified stem cells to improve allograft revitalization and bone healing in cancer patients that may lead to limb preservation; use of pre-activated mesenchymal stem cells to treat orthopedic hardware associated infection in humans; use of stem cells to treat inflammatory bowel disease; and the use of natural animal models in regenerative medicine to accelerate successful translational research. The target audience is laboratory animal professionals, researchers, and technicians.

Speakers/Topics:

8:00Sue VandeWoudeWelcome and Introductions
8:05Sue VandeWoudeWhat is Zoobiquity?
8:25Nicole EhrhartGenetically Modified Stem Cells for Limb Preservation in Canine Oncology Patients
8:55Laura DamioliStem Cell Therapy for Management of Orthopedic Infections
9:25Tracy Webb"Animal Farm" Revisited: Learning from Naturally Occurring Disease Models in Animals
This Seminar is sponsored in part by ACLAM/ASLAP Joint Committee.


PLATFORM SESSIONS

8:00 AM-10:45 AM

Platform Session abstracts will be available on www.aalas.org in July. They will also be included in both the mobile app and the National Meeting Final Program.


PANEL DISCUSSION


Pathology Quiz Bowl
8:30 AM - 10:00 AM/Room: Mile High Ballroom 3A
Leader: Cynthia L Besch-Williford
Moderator: Craig L Franklin
Facilitator: TBN
Panelists: Marcia L Hart, Craig L Franklin, Angela K Brice, Cynthia L Besch-Williford

This panel discussion will consist of an informal review of the pathology of laboratory animals in the form of an image-based quiz. Topics will include lesions of well-described infectious and noninfectious diseases, pathological manifestations of emerging diseases, and selected phenotypic characteristics of important genetically engineered animal models. The images will be educational and challenging to laboratory animal specialists at all levels of pathology expertise. Targeted audience is comparative medicine trainees, laboratory animal veterinarians, pathologists, and scientists. Participants from comparative medicine training programs have the opportunity to receive a fabulous cash prize for the highest score. A participation cash prize is also provided. The comparative medicine trainee with the highest score will be recognized at the Committee for Laboratory Animal Training and Research (CLATR) luncheon on Tuesday. Participants will learn gross and histologic pathology of laboratory animals. Pathology Quiz Bowl is co-sponsored by CLATR and IDEXX BioAnalytics.

This Panel Discussion is sponsored in part by IDEXX BioAnalytics and Committee for Laboratory Animal Training and Research (CLATR).

SPECIAL TOPIC LECTURES


ACLAM Diplomates in the West African Ebola Response

11:00 AM - 12:00 PM/Room: Mile High Ballroom 2A
Speakers: Brianna L Skinner, Temeri Wilder-Kofie
Moderator: Kathy Laber
Facilitator: TBN

The 2014-2015 Ebola outbreak in West Africa (Margibi County, Liberia) was the worst Ebola public health crisis in recent history. Two laboratory animal medicine United States Public Health Service Officers were deployed to West Africa with the purpose of working in an Ebola Treatment Unit designed to care for healthcare workers with suspected and confirmed cases of Ebola. This session highlights and describes the roles of the veterinarians, the response mission, and their overall experiences during the crisis.

Charles C Hunter Lecture: Bison, Brucellois, and Baby-Making

11:00 AM - 12:00 PM/Room: Mile High Ballroom 1A
Speaker: Jennifer Barfield
Moderator: Christian Stoffers
Facilitator: TBN

The North American bison is a symbol of the American West and Native American culture. This majestic animal that once roamed the plains in the tens of millions has survived a storied yet tragic past. While conservation efforts have succeeded in bringing bison back from the brink of extinction, there are still important efforts being made to secure the species into the future. Come hear the story of one such effort that is using assisted reproductive technologies to circumvent disease and preserve the genetic lineage of bison from Yellowstone National Park. This talk could be of interest to anyone attending the AALAS National Meeting. It will appeal to the technicians, as well as researchers and veterinarians.

This Special Topic Lecture is sponsored in part by Committee for Technician Awareness and Development (CTAD).

DEA Rules and Regulations

11:00 AM - 12:00 PM/Room: Mile High Ballroom 4A
Speaker: Daniel J McCormick
Moderator: Jennifer L Asher
Facilitator: TBD

Many controlled substances, including opioids, are powerful analgesics, but also have serious risks of addiction, abuse, and overdose. Security, recordkeeping, and reporting are all requirements when a person obtains a Drug Enforcement Administration (DEA) registration to handle controlled substances. Staying aware of the current requirements for dispensing, documenting, and continuing education related to controlled drugs can be overwhelming. This presentation will detail security requirements for researchers using controlled substances. The various recordkeeping requirements for researchers will be covered, and the types of reports that must be submitted to the DEA by researchers will be discussed. In addition, current trends in drug diversion will be covered to help researchers better recognize possible diversion in their own facilities. Participants will learn about the current DEA rules and regulations, how to abide by the laws within laboratory animal medicine, and how abuse of controlled substances can affect those in the veterinary profession. The target audience is anyone working with controlled substances, including researchers, veterinarians, veterinary technicians, managers, and supervisors.

Does Relative Humidity Affect Reproducibility of Research?

11:00 AM - 12:00 PM/Room: Mile High Ballroom 3A
Speaker: Preben Leonhardt
Moderator: Kari Koszdin
Facilitator: TBD

Relative humidity levels below 30-40% in the laboratory rodent facility may increase the risk of certain physiological conditions in mice and rats, including skin and eye conditions and a delayed puberty in female mice. Likewise, a relative humidity level above 60-70% seems to induce the first estrus earlier in mice and may induce a favorable environment for unwanted pathogens. Ongoing studies show interesting preliminary data on rodent welfare and physiology when relative humidity is locally, accurately controlled with an accuracy of ±3% compared to when relative humidity is controlled centrally, and thus fluctuating with the variable weather conditions. In a UK facility when tightly controlling relative humidity the amount of water mice drank changed in response to changes in relative humidity. Therefore, it might be important to control relative humidity levels if water or food intake or water restriction are parameters in your study. A facility in Finland found a significant reduction in preweaning mortality of pups from genetically altered mouse strains when relative humidity was kept stable at 55% compared to room-controlled humidity. Likewise, a study in a UK mouse facility has been looking at the effects of improved control of relative humidity on breeding parameters in mice. At the same facility, a study was conducted to investigate the effects of relative humidity controlled at 55% on embryo transfer in mice. A current study in Austria is investigating the impact of accurately controlled relative humidity on breeding parameters in mice and aggression in male mice. Preliminary results have suggested a positive effect on both parameters. We will present our findings and discuss the impact of obtaining controlled relative humidity in the rodent facility. The target audience is researchers, facility managers, veterinarians, and animal caretakers.


MONDAY AFTERNOON

PANEL DISCUSSIONS


21st Century Cures Act: Where Are We Now?

12:30 PM - 2:00 PM/Room: 401
Leader/Moderator: Aubrey Schoenleben
Facilitator: TBN
Panelists: William G Greer, Sally Thompson-Iritani, Patricia A Brown, USDA Representative (TBN)

The 21st Century Cures Act, Section 2034(d) directed federal agencies to “complete a review of applicable regulations and policies for the care and use of laboratory animals and to make revisions, as appropriate, to reduce administrative burden on investigators while maintaining the integrity and credibility of research findings and the protection of research animals.” In response, a working group was convened that included representatives from NIH, USDA, and the FDA. The working group employed several strategies to identify regulations and policies that contribute to administrative burden, such as reviewing published reports and surveys on the topic, hosting listening sessions, and collecting feedback from the public through a request for information. A draft report detailing the working group’s suggestions was released for public comment earlier this year. We will provide an update on the status of the 21st Century Cures Working Group report, including discussion on upcoming changes to regulations and policy, how federal agencies are improving coordination and harmonization, and new training and resources being developed. Panel members will also discuss how institutions can implement some of the proposed suggestions for reducing burden, such as the use of best practices offered through the IACUC Administrators’ Association and standard procedures included in the Federal Demonstration Partnership’s CUSP project.

Adding Your Voice to Social Media: Five Steps to Navigate This Important Outreach Too

12:30 PM - 2:00 PM/Room: 403
Leader/Moderator: Crister DelaCruz
Facilitator: Wendy R Williams
Panelists: Lisa Newbern, Rachelle L Stammen, Paula A Clifford

Social media is a powerful outreach tool. The peer-to-peer communications platform can be used to share information broadly or to specific audiences. Our society demands cures and treatments for their loved ones, which requires animal studies. At the same time, we are all rightly concerned about animal welfare. Discussing animal research on social media helps educate others, one story at a time, about the essential role of animals in advancing science and medicine. Equally as important, it helps us demonstrate the compassionate care that these animals receive. This session will provide five simple tips on how to effectively communicate about animal research with online audiences. The first tip focuses on developing your message. This will include what types of stories to share, how to use real-life examples to genuinely get your message across and the importance of focusing on the science, as well as animal care. The second tip will delve into institutional policies around social media and what in-house resources are likely available for support. The third tip focuses on how to have productive conversations and address negative comments. The fourth tip offers advice on where social media communicators can find external support through advocacy groups and other organizations. The fifth tip will wrap up the session by giving participants advice on determining which platform best fits one’s personal outreach goals. An expert panel consisting of advocacy professionals, a university communications expert and a laboratory animal veterinarian will offer a variety of perspectives and advice for attendees. The targeted audience is anyone interested in talking about animal research online.

This Panel Discussion is sponsored in part by ACLAM/ASLAP Joint Committee.

Animal Nursing Challenges in the Research Setting: Communicating, Collaborating, and Coordinating to Achieve Optimal Health Outcomes for All

12:30 PM - 2:00 PM/Room: 501
Leaders: Chrystal L Montgomery, Mark Sharpless, Phillip N Sullivan, Beth Ann Skiles
Moderator: Ann L Murray
Facilitator: Summer M Boyd
Panelists: Chrystal L Montgomery, Mark Sharpless, Phillip N Sullivan, Beth Ann Skiles

The interconnection between human health, animal health, and the environment is complex, delicate, and often complicated. Successful management of these relationships and interactions and compassion fatigue require careful oversight and thoughtful consideration. Societal standards and expectations for quality care and ethical treatment of human and nonhuman patients are equivalent today. In addition, outcomes that result from these interactions have global community impact. This panel will discuss and explore the intricate relationships and challenges that each part of the animal nursing team encounters over the life of the study from the perspective of veterinary nurse. Biomedical research uses animal models that range from complex organ transplant models in USDA-covered species all the way down to basic life sciences in invertebrate models. Over the course of the study, various challenges always inevitably arise posing challenges and frustrations to the veterinary, animal care, and regulatory staff. These challenges combined with the human-animal bond the staff have with these animals can lead to burnout and compassion fatigue as well as decreased efficiency and effectiveness. Addressing nursing complications from the beginning of study design to the completion of the study will help reduce burnout and compassion fatigue. Additionally, addressing compassion fatigue throughout the various phases of the study will help reduce nursing complications. Staff members involved with a study that are able to coordinate, communicate, and collaborate will provide high-quality care and innovative approaches throughout the life of the study. In tackling nursing challenges from this one-team approach, we hope to provide veterinarians, veterinary technicians, animal care staff, research staff, and regulatory staff a different approach to solving problems and overcome nursing challenges that come up daily in biomedical research.

This Panel Discussion is sponsored in part by Academy of Laboratory Animal Veterinary Technician and Nurses.

Groundhog Day: Learning from Leadership Failures—What Not to Do

12:30 PM - 2:00 PM/Room: 503
Leader: Donna M Jarrel, Jarrod Nichol
Moderator: Gerard M Cronin
Facilitator: Patricia M Holly
Panelists: Sharron M Kirchain, Sai Tummala, David W Brammer, Ron P Wilson

“I woke up one morning and realized I was solving the same problems for 32 years” is an actual quote shared by a senior ICU nurse. But it could be said by anyone of us in management or research. When every day seems like Groundhog Day, it may be time that we think of change. Managing change is one of the most treacherous experiences leaders face today when working to improve your culture and operations. Poorly executed initiatives or murky communication can taint the trust from your managers, staff, and your customers. We all love to talk about our successes, but we hardly ever talk about our challenges and failures, which is when our greatest learning and growth happens. Four leaders from a variety of research programs will provide their reflections and lessons learned in situations where communication or implementation went sour, how they recovered, and how they would approach it again if they had the chance. Attendees will also learn insights, tools, and tricks on how to overcome everyday operational problems that seem to suck the oxygen out of our time and energy. The targeted audience is directors, leadership, facility managers, program managers, supervisors, and future leaders. Attendees will learn management challenges and missteps are inevitable. Knowing the tools and techniques to deal with those challenges can be the difference between being an effective or ineffective leader and trust building with staff and customers. Presenters will share their challenges or mishaps and what techniques they have learned to use to improve their organizational effectiveness.

This Panel Discussion is sponsored in part by Vivarium Operational Excellence Network.



WORKSHOPS


W-05 Animal Facility, Design, Processes, Decisions, and Technology

1:00 PM - 5:00 PM/Room: 302
Leader: Mark Corey
Faculty: Lauri Tyrrell, Chad Zuberbuhler, Clifford R Roberts, Laura Halverson, Kathleen L McGimpsey
Facilitator: Trinka W Adamson
Workshop Fee: $150 Workshop Limit: 50

This workshop will benefit those involved with animal facility design and operations by describing the process, decisions, and technologies involved in the design and construction. The session will begin with a discussion of the facility design process—who should be involved, the objectives and level of effort by stakeholders, milestone decisions to be reached, and anticipated duration of the various phases of the process. Current trends in the industry will be explored through discussions about planning, interior construction, acoustics, and finishes. Throughout the session we will be framing the discussion from the owner’s perspective and their experiences in the real world. We will include critical mechanical, electrical, and piping design and operations. This section will focus on the MEP risks associated with compromised animal welfare, loss of research and facility resiliency, and how engineering decisions affect each of these parameters. The lessons learned will help enable participants to make more informed decisions as they develop and operate their own facilities. Conversations will focus around vivarium operations and facility sanitation and safety. We will also discuss strategies regarding energy and water conservation that are being effectively implemented in animal facilities and the derived long-term benefits.

W-06 Leading the Self and Others with Emotional Intelligence

1:00 PM - 5:00 PM/Room: 303
Leader/Faculty: Jamie Mueller
Facilitator: Sarah Hansen
Workshop Fee: $150 Workshop Limit: 50

The first person you lead is yourself. We know that meaningful and sustainable leadership works through emotions. This workshop will increase participants awareness and understanding of emotional intelligence based on the Goleman model, have them explore the leadership competencies of emotional intelligence and provide them insight on how leaders handle themselves and their relationships. Specifically, participants will develop their awareness around emotional intelligence skills, specifically around self-awareness, self-management, social awareness and relationship management; define their own leadership strengths and style; and understand alignment between their values and leadership behavior. The workshop is targeted to leaders, directors, and managers who are in an existing leadership role or will be in the future and wish to better understand the key competencies necessary to lead in today's fast paced and ever-changing environment.

W-01B Microsurgery Skills Training Using Surgical Loupes (offered twice, also Monday 8:00 AM)

1:00 PM - 5:00 PM/Room: 301
Leader: Robert F Hoyt Jr
Faculty: Robert F Hoyt Jr, Randall R Clevenger, Timothy J Hunt, Karen Keeran, Tom Thomas, Tannia Clark, Elena Kuznetsova, Gayle Nugent, Victoria L Haley, Kenneth Jeffries, Tanya Herzog, Audrey Noguchi
Facilitator: TBN
Workshop Fee: $250 Workshop Limit: 20
See Monday AM for description.

This Workshop is sponsored in part by Q-Optics, RICA Surgical Products, SurgiReal Products, Inc., and Supramid Suture.

W-07 Teaching Monkeys to Cooperate with Restraint: Using Positive Reinforcement Training and Temperament Testing Methods

(8-hour workshop continued Tuesday 8:00 AM)
1:00 PM - 5:00 PM/Room: 607
Leader: Jaine E Perlman
Faculty: Jennifer L McMillan, Kristine Coleman, Mollie A Bloomsmith
Facilitator: Mark J Prescott
Workshop Fee: $250 Workshop Limit: 50

The workshop includes instruction on using positive reinforcement training (PRT) to teach monkeys to cooperate with various restraint procedures and provides information on using temperament testing to assist in selection of subjects and planning for their training. Participants will learn approaches to training laboratory primates to cooperate with restraint for sample collection and administration and for chair restraint. PRT is an important refinement in the care of nonhuman primates and an effective means of improving their welfare. However, animals respond differently to restraint and measuring temperament provides insight into how individuals might respond to these procedures, allowing for individualized and more effective training plans. The goals are to introduce participants to animal training terminology and technique, to teach PRT techniques as they apply to restraint procedures, such as the use of the cage squeeze back mechanism and chair restraint, and to teach methods to assess and quantify temperament in monkeys and to use this information to develop individualized training plans. Participants will learn how to establish a strong foundation for successful restraint training using PRT techniques, and how to incorporate alternative techniques such as negative reinforcement to meet research timelines. They will learn to identify monkeys who are engaged in the training process and how to increase the involvement of monkeys who seem uninterested in training. Participants will learn how to shape behavior and apply desensitization techniques, how to maintain trained behaviors over time, and how to transfer trained behaviors among multiple staff members. Participants will learn how temperament can impact training approaches and the anticipated timelines for training to cooperate with restraint. This workshop is designed for those experienced in working with primates including behavior specialists, animal caregivers, research technicians, animal managers, veterinarians, and investigators.

This Workshop is sponsored in part by Lomir, Hybex, Britz & Company, Carter2Systems, NC3Rs and NC3RsC.

W-08 Vivarium Ergonomics: Establishing and Effective, Sustainable Program

1:00 PM - 5:00 PM/Room: 304
Leader: Terry Snyder
Faculty: Jennifer S Kilpatrick
Facilitator: TBN
Workshop Fee: $150 Workshop Limit: 50

Are you concerned about the high injury rate of your vivarium staff? If so, you are not alone, as these jobs are high risk for injury, pain, and discomfort. This can lead to loss of experienced employees, costly workers compensation claims, and negative impact on morale, quality, and productivity. A robust ergonomics program can successfully address these problems. Using practical examples of animal care technician job tasks, this workshop will introduce participants to common risks for musculoskeletal injury and effective improvement methods. But identifying problems and solutions is only the first step in addressing this problem; how often has your facility tried to make changes to improve ergonomics only to find that the new procedures or equipment are not being used? This workshop will also explore effective strategies and methods for employee engagement and steps to establishing a successful program of continual, sustainable improvement. This program is for vivarium managers, supervisors, lead technicians, trainers, animal care and veterinary technicians, as well as occupational health and safety personnel.


PLATFORM SESSIONS

2:15 PM-5:00 PM

Platform Session abstracts will be available on www.aalas.org in July. They will also be included in both the mobile app and the National Meeting Final Program.

SEMINARS


Fish Health Monitoring: Facilitating for One Health
2:45 PM - 5:00 PM/Room: Mile High Ballroom 2A
Leader: Jean-Philippe Mocho
Moderator: Katy Murray
Facilitator: Michael L Kent

Research on fish addresses the One Health concept through various angles, such as impact of environmental pollution on wild fish populations, toxicological screening on embryonic or larvae forms, and pathogenicity of zoonotic infections like mycobacteriosis. Considering the rapid expansion of fish research, it is time to reflect on how to nurse the animal models, meaning protecting fish from disease and pathogen contamination and to protect staff from zoonosis. In this seminar, first the interference between fish disease and research endpoints will be detailed. Then, we will focus on aquatic zoonotic mycobacteriosis. These fish and human pathogens invade a wide range of media (environmental reservoir, fish, live feed) and therefore constitute a non-neglectable hazard for aquatic staff and models. Finally, a transcontinental working group (FELASA-AALAS) was constituted to recommend good practices of fish health monitoring. The outcome of its deliberations will detail how to determine the number of fish and environmental samples to screen in a zebrafish facility and what a specific-pathogen free (SPF) status would entail regarding quarantine and biosecurity. The presentations will be followed by a discussion highlighting the challenges of implementing fish health monitoring according to the facility setup, internal policies, and researchers’ interests and goals. The target audience (animal care givers, veterinary staff, facility managers, and researchers) will be given the opportunity to understand how fish diseases can be monitored and how strict biosecurity measures will help protect fish and staff against relevant contamination.

Speakers/Topics:

2:45Katy MurrayWelcome and Introductions
2:50Katy MurrayDisease Impact on Research Endpoints
3:20Christopher WhippsEpidemiology of Aquatic Zoonotic Mycobacteriosis: Environmental Reservoir and Transmission
3:50J-P MochoFELASA-AALAS Working Group Recommendations for the Health Monitoring of Fish in Research


One Health: Roots to Flowers

2:45 PM - 5:00 PM/Room: Mile High Ballroom 1A
Leader/Moderator: James Owiny
Facilitator: Alexa Personett

The tripartite of environment, human, and animal health interactions is central to One Health. These long-term interactions hinge on a delicate balance between multiple factors, including host defenses, pathogen virulence, nutritional state, environmental disturbance, and population density. A shift in any of these components leads to insidious health effects in humans, animals, and the environment. We will discuss current research on emerging and reemerging health problems from bench top to nontraditional animal models, community education and empowerment, and manufacture of new therapeutic agents (biologics) for human clinical trials. We begin by highlighting the psychological impacts of the uranium disaster among the Navajo people, its impact on the health and wellbeing of the Sweetwater Chapter community of the Navajo Nation, and the need for enhanced information about toxic exposure to people, animals, and the natural environment to facilitate decision-making and advocacy. Then we present development of an animal model for understanding the pathogenesis of MERS CoV and a potential strategy to break the transmission cycle. We explore ways to prevent the transmission of mosquito-borne diseases by targeting the blood meals the mosquitoes ingest by using endectocidal drugs to control the transmission of malaria and West Nile virus. Next, we discuss empowering Nepalese women to use smartphones equipped with disease-reporting software to enable a bottom-up approach to reporting livestock diseases to facilitate identifying and controlling disease outbreaks. Finally, we illustrate development and manufacture of new biopharmaceutical products for nonclinical and clinical trials under stringent containment and biosecurity conditions. The target audience is laboratory animal professionals, scientists, and technicians.

Speakers/Topics:

2:45James OwinyWelcome and Introductions
2:50Gilbert JohnA One Health Approach to the Effects of Legacy Uranium Mining on the Navajo Nation
3:15Danielle AdneyMERS-CoV: Camels in Colorado?
3:40Brian FoyWatch Out for Mosquitoes: West Nile Virus and Malaria
4:05Richard BowenEmpowering Women for Detection and Reporting of Livestock Disease
4:30John WyckoffManufacturing Biologics for One Health Measures


Rodent Infectious Agents: The New Unknown, the Impact of Metagenomics
2:45 PM - 5:00 PM/Room: Mile High Ballroom 4A
Leader/Moderator: Neil S Lipman
Facilitator: Mandy L Kain

Most of the infective agents we recognize today, whether they are primary pathogens, opportunists, or commensals, were identified as they were cultivatable, observable, and/or shared features with agents identified using the former methods. The advent of metagenomics has changed this paradigm. Metagenomics, a broad variety of research techniques using molecular biological methods to identify communities of organisms at the genomic level, has become an increasingly important tool in the identification of novel microbial agents, both those associated with changes in the host, as well as those of unknown or undefined significance. Metagenomics is already having a significant impact in laboratory animal science and this impact will certainly increase. The speakers will review metagenomic methods and how they can and have been employed to answer important questions. Novel information will be presented on several rodent viruses recently identified using metagenomics, notably murine astrovirus, mouse kidney parvovirus, and rat polyomavirus, as well as many previously unrecognized viruses found in wild Mus musculus. The seminar will conclude with a discussion in which the presenters will deliberate as to what criteria the laboratory animal science community should consider using to determine whether a specific agent is of sufficient concern, that its presence should be identified, and when it should be excluded. This seminar will be of considerable interest to many meeting attendees as novel information will be presented on three emerging laboratory rodent viruses as well as other viruses that can potentially infect the laboratory mouse.

Speakers/Topics:

2:45Neil LipmanWelcome and Introductions
2:55Kenneth S HendersonSolving Diagnostic Challenges with Metagenomics
3:30Rodolfo RicartThe Serendipitous Discovery of a Novel Murine Astrovirus
3:45Sean P KellyMuAstV2: An Unusual Virus that Requires an Intact Immune System
4:10Cynthia L Besch-WillifordRatPyV2: Evidence for Polyomaviral Persistence in Infected Immunocompetent Rats
4:35Simon WilliamsInterrogating NYC "Street" Mice
Valuing Emotional Labor in Animal Facilities

2:45 PM - 5:00 PM/Room: Mile High Ballroom 3A
Leader: Bella Williams
Moderator: Kathryn Bayne
Facilitator: Ghislaine Poirier

Often under recognized, the strong emotions experienced daily by those working in animal facilities form a key part of their role. The way that all staff manage, express, and share their emotions with one another can lead them to bond closely, care for their animals with deep compassion, and form a basis for an institutional culture of care. When not provided with outlets, support, or recognition of their emotional challenges, both daily work and institutional culture can be affected, leading to the hallmarks of compassion fatigue, including guilt, emotional burnout, and sickness. Three speakers will present their take on the emotion-work carried out in animal facilities and how it can be effectively recognized to support staff and provide better care for the animals. They will consider the emotional cost of caring, why it is so important to our work, and recent developments in our understanding of care as a vital component in the well-being of facility staff and animals. We will present three examples of initiatives that recognize and support those whose work involves care, including implementing regular one-to-one discussions, a developing a Culture of Care Pledge, and establishing a memory garden. These different approaches reflect different practicalities and organizational cultures, and we will cover their development and outcomes of the initiative to date. We all need an outlet, and one of these approaches may work for your organization, or you may be inspired to develop something completely new. In this session we will learn about the importance of recognizing and valuing emotional labor, and approaches that can help to develop emotion-work and care as an asset, rather than a cost, of working in an animal facility. The target audience is facility managers, veterinarians, and technical staff.

Speakers/Topics:

2:45Kathryn BayneWelcome and Introductions
2:50Bella WilliamsEmotional Labor, Responsiveness, and Animal Use
3:25Joy RedmondPreventing Compassion Fatigue through Establishing a Memory Garden
4:00Matthew GallacherEstablishing a Culture of Care at AstraZeneca