MONDAY MORNING


WORKSHOPS

W-01 Anesthetic Monitoring 101—Back to Basics

8:00 AM - 12:00 PM/Room: 345
Leader: Cholawat Pacharinsak
Faculty: Tyler Long
Facilitator: Sean C Adams
Workshop Fee: $140 Workshop Limit: 25

Attendees will become familiar with anesthetic monitoring during peri- and post-operative periods which alert anesthetists to potential complications before they become irreversible, thus reducing morbidity or mortality. During peri-operative period, many parameters should be monitored, including central nervous system, cardiovascular, and respiratory functions. The workshop will focus on the basic understanding and importance of commonly used anesthetic monitoring equipment (ECG, blood pressure, %SpO2, ETCO2, and body temperature) for indications, implementations, and interpretations during large animal anesthesia. The workshop will be conducted in an easy-to-understand manner. This dry lab workshop is appropriate for veterinarians, laboratory animal technicians, scientists, laboratory managers, and IACUC members who are not familiar with basic anesthetic monitoring techniques.

This Workshop is sponsored in part by Kent Scientific and VetEquip Inc.

W-02 CMAR/Animal Resource Exam Prep Class (8-hour workshop continued Tuesday 8:00 AM)

8:00 AM - 12:00 PM/Room: 346
Leader: Diana P Baumann
Faculty: Diana P Baumann, Camellia M Symonowicz
Facilitator: TBD
Workshop Fee: $140 Workshop Limit: 50

We are heroes to millions of people and animals, and our work makes a profound difference in this world. As leaders, we have a responsibility to support and drive our employees and operations effectively, efficiently, and compassionately. CMAR certification provides us with a unique set of knowledge and tools. The Laboratory Animal Management Association (LAMA) has developed a workshop for the CMAR exams, designed for your success. Please join us for our preparatory workshop for the Animal Resource (AR) exam. Topics covered include effective management styles and motivating the workforce, training and education for laboratory animal professionals, managing physical resources, policy development, managing budgets, veterinary care, IACUC, and managing compliance. This prep course alone will not prepare you for the AR exam, but provides a refresher and review of your existing studies.

W-03A Microsurgery Skills Training Using Surgical Loupes (offered twice, also Monday 1:00 PM)

8:00 AM - 12:00 PM/Room: 347
Leader: Robert F Hoyt Jr
Faculty: Tannia S Clark, Randall R Clevenger, Tanya L Herzog, Kenneth R Jeffries, Karen J Keeran, Elena Kuznetsova, Audrey Noguchi, Gayle Z Nugent, Tom L Thomas
Facilitator: Misty J Williams-Fritze
Workshop Fee: $250 Workshop Limit: 20

Performing surgical procedures with the aid of magnification has gained widespread use in human medicine over the past 30 years. Using surgical loupes, surgeons can now routinely perform procedures on very small structures that were considered impossible a few decades ago. Within the past 15 years, using magnification to perform microsurgical techniques has also quickly spread to other health care disciplines, including dental specialties and dermatology, to increase surgical precision. Using them is now considered standard of care. The use of microsurgery and its value to biomedical research has, unfortunately, only just begun to be realized. Because of their small body structures, laboratory animals, such as rats and mice, have generally not been considered as animal models for many types of surgical procedures routinely performed in biomedical research. Investigators have rather elected to use larger species such as dogs, pigs, sheep, rabbits, or nonhuman primates for such modeling because both surgical support equipment is more readily available, and the surgical techniques are more familiar to the support personnel. The recent shift to using genetically engineered rodents, especially mice, has now resulted in increased researcher desires to use these animals in more sophisticated modeling procedures, especially surgery. Rather than being limited to only simple procedures such as IM, IP, or IV injections, researchers using microsurgery can now perform complex surgical procedures on many rodent organ systems, such as the heart, lungs, and the gastrointestinal tract. This workshop will provide an introduction to the basic techniques, equipment, and general applications of microsurgery using surgical loupes. Hands-on training will be conducted in two phases: 1) teaching students to develop technical skills by performing exercises using surgical loupes and 2) applying these skills to perform simple surgical procedures using rodent and organ surrogates. To enhance student success, we have greatly enhanced the teacher: student ratio. Targeted audience is veterinarians, investigators, technicians.

This Workshop is sponsored in part by Midwest Veterinary Supply, Q-Optics Surgical Loupes, SurgiReal Products Inc, Supramid Suture and RICA Surgical Products.

W-04 Technician to Supervisor: Management 101: The Ups and Downs of Managing People

8:00 AM - 12:00 PM/Room: 349
Leader/Faculty: Stephen T Baker
Facilitator: Leah Curtin
Workshop Fee: $140 Workshop Limit: 50

When you excel at a technical skill or provide superior husbandry/study support, individuals are often rewarded with a promotion that expands their role and responsibility to include managing others. Individuals whose primary focus/expertise is animals are asked to change gears and channel their soft skills. This workshop will provide a high level overview/introduction of key concepts to support a successful transition. Topics will include performance management, effective interviewing skills, hiring and firing, how to handle conflict, coaching versus delegating, and how to communicate effectively. This interactive workshop will take participants through various exercises, role plays, and what-if scenarios to provide take-aways which can be applied back at their place of employment. The targeted audience includes new supervisors or first-level managers. If you are new to the world of managing others or contemplating getting into management, you do not want to miss this workshop.

This Workshop is sponsored in part by Pfizer, Inc.

SEMINARS


A Day in the Life with our "Funny Little Creatures"
8:00 AM - 10:15 AM/Room: Ballroom I
Leader/Moderator: Sylvia I Gografe
Facilitator: Carrie S List

This seminar will appeal to a broad audience as we take you on a journey through our world of working with nontraditional species, or as we like to call them, our funny little creatures. It’s not only interesting and informative, it’s exciting, fun, and there is rarely a dull moment. No matter what your role is at your specific institute you will be surprised at the ideas and inspirations these models can provide. We will get those creative juices flowing and help you implement some of the presented work solutions in your job and learn that nothing is impossible when providing the best care for our animals! Interesting questions will be answered such as why are they called tree shrews if they don’t live in trees, they’re not shrews, and they’re not “Scrat” from the movie Ice Age, but they are developing into one of the most sought after research models; why an odd-looking Egyptian rodent emerged as an attractive alternate model for Leishmania research; how food-caching birds, such as wild-caught black-capped chickadees and the tufted titmouse make useful models for studying memory; and in which way regulation EU Directive 2010/63 now covering cephalopods incited the development of Best Practices for husbandry of these highly intelligent critters and their caregivers’ training. The speakers will not only focus on husbandry, care, and health but also safety and regulatory challenges, the often-unconventional solutions, and of course the exciting research topics involving these species. As everyone can imagine, solving the aforementioned problems can be time-consuming; however, nontraditional species catch our attention and reward us for our efforts. So please join us on our journey and enjoy the stories, pictures, and presentations about our funny little creatures.

Speakers/Topics:

8:00 Sylvia I GografeWelcome and Introductions
8:10 Susan FrelingI Didn’t Pick the Shrew Life, the Shrew Life Picked Me
8:40 Stephen FeltFat-tailed Jirds (Pachyuromys duprasi): Fantastic Beasts and How to Care for Them
9:10 Viola Galligioni and Graziano FioritoPursuits on Cephalopod Care and Proper Personnel Training
9:40 Christina L Winnicker Wild Feathers: Working with Black-capped Chickadees (Poecile atricapillus) and the Tufted Titmouse (Baeolophus bicolor)

Are Times Changing in the Animal Research Oversight Environment?

8:00 AM - 10:15 AM/Room: Ballroom II
Leader/Moderator: B Taylor Bennett
Facilitator: William S Stokes

Section 2034 of the 21st Century Cures Act (Cures), signed into law on December 13, 2016, directs leadership of NIH, USDA, and the FDA to “complete a review of applicable regulations and policies for the care and use of laboratory animals and make revisions, as appropriate, to reduce administrative burden on investigators while maintaining the integrity and credibility of research findings and protection of research animals.” The review is to be completed within two years of the bill’s enactment. On July 17, 2017, the Department of Agriculture issued a Request for Information (RFI) entitled “Identifying Regulatory Reform Initiatives” and on January 22, 2018, an announcement entitled “Third-Party Inspection Programs Under the Animal Welfare Act; Public Meetings.” These events could lead to changes in the current oversight environment that impact how animal care and use programs are managed. This seminar will provide the attendees with an opportunity to hear from representatives of the USDA, OLAW, AAALAC, and NABR regarding possible changes, as well as other ongoing issues, within their organization and to discuss with those representatives how their organization’s activities impact the environment in which we work and what changes to expect in the future. Questions for the panelists can be submitted to btbdvm@yahoo.com. The target audience will be those who need to keep current with the regulations and requirements for conducting animal-based biomedical research.

Speakers/Topics:

8:00 B Taylor Bennett Welcome and Introduction
8:10 Elizabeth Goldentyer USDA Update
8:30 Patricia Brown OLAW Update
8:50 Kathryn Bayne AAALAC Updatge
9:00 Matthew Bailey NABR Update
9:30 B Taylor Bennett Discussion

This Seminar is sponsored in part by National Association for Biomedical Research (NABR), United States Department of Agriculture (USDA), APHIS Animal Care and National Institutes of Health Office of Animal Care, and AAALAC International.

Reproducibility: From the Tank/Cage Side for Better Research and > 3Rs
8:00 AM - 10:15 AM/Room: Ballroom III
Leader/Moderator: John J Hasenau
Facilitator: Stephanie J Murphy

This seminar will consider practical options to achieve better research reporting and reproducibility. Participants will learn about reporting of environmental conditions for animal research models and next steps to ensure more rigorous reporting. We will review historical concerns and contemporary issues going forward. Last year's AALAS meeting included much discussion on research reproducibility and opportunities for improvements. We will review developments and usage of reporting guidance and update a 2017 survey on the use of these guidelines. An area with minimal reporting has been laboratory fish housing, husbandry practices, and environmental parameters, which are highly variable and are under-reported. Environmental factors are under-recognized as contributors to experimental variation, and this information is rarely shared or requested. The problem was addressed by 1) developing a summary environmental report for research fish facilities, and 2) disseminating these data by depositing this document into an accessible web-based platform for data sharing called protocol.io. In addition, pharmaceutical companies and CROs contend with regulatory requirements that involve extensive QA QC and documentation that includes macro- and micro-environmental data collection and reporting. We will present examples of the practical application of digital information within a unit, and across a global organization, and its effects on study reproducibility. Husbandry impact on reproducibility and data consistency is addressed by the last speaker. While “meets Guide standards” is the company line, the details of daily care vary among institutions. Differences in cage components, housing density, cage changing frequency, and practices are all recognized to impact animal development, physiology, and behavior. Suggestions to improve reproducibility of rodent research will be presented. A discussion based on audience questions will end the session. The target audience includes all individuals engaged in research involving animal models including animal facility managers, lab animal and research technicians, staff, veterinarians, IACUC members, scientists, and editors, reviewers, and authors.

Speakers/Topics:

8:00 John J Hasenau Welcome and Introduction
8:05 John J Hasenau Study Reproducibility Overview
8:15 Cory F Brayton Guidelines for Reporting: What, Where, When?
8:40 Christian Lawerence Environmental Summary Reporting: A Tool for Improving the Reproducibility of Zebrafish Studies
9:05 Szczepan BaranInnovation and Quality Initiatives for Reproducibility of Studies
9:30 Samuel C Cartner Cage Side Care that Impacts Consistency and Reproducibility of Rodent Research
9:55 John J Hasenau Discussion


Tours of Animal Research Facilities as Opportunities for Public Engagement

8:00 AM - 10:15 AM/Room: Ballroom IV
Leader: Sarah O Allison
Moderator: Paula A Clifford
Facilitator: Jim Newman

Some research organizations have successfully established tour programs at their animal research facilities and maintained these efforts for many years. Others are now considering the possibility of incorporating this form of increased transparency into their organizations as an effort to proactively engage the public about why, when, and how animals are needed in research. At organizations where visitors are allowed, the experience—both for tour providers and tour participants—is almost always very positive. Tour attendees were able to gain both knowledge about why animals are essential in research and how these animals are cared for. The experience also provided research and/or animal care staff the chance to proudly discuss their work. Best of all, tour participants gained the intangible, long lasting benefit of seeing first-hand the extent in which the laboratory animal community ensures compassionate care and the best environment possible for the animals. Participants will learn perspectives on how tour programs were launched and maintained at two academic facilities, a biopharmaceutical company, and a contract research organization. They will also learn how each manages their tour programs and how they sought and obtained institutional and administrative approval. In addition, participants will engage in a discussion to gain practical advice and recommendations on hosting animal research facility tours at their own institutions. The target audience is anyone interested in, or charged with, institutional outreach efforts, those considering providing tours as part of internal or external outreach, and those who are looking to improve or share their experience with providing animal research facility tours.

Speakers/Topics:

8:00 Paula A Clifford Welcome and Introduction
8:15 Sarah O Allison Students as new PIs: An Innovative Format for Animal Research Facility Tours
8:45 Paige A Ebert Outstanding Outreach: To Tour or Not? A Biopharmaceutical Perspective
9:15 Jessica L Hendricks Hosting Animal Research Facility Tours at a Contract Research Organization
9:45 Tiffany L WhitcombStudent-Centered Approach to Facility Tours at an Academic Research Institution
This Seminar is sponsored in part by Americans for Medical Progress (AMP) and AbbVie.


PLATFORM SESSIONS

8:00 AM-10:45 AM

Platform Session abstracts will be available on www.aalas.org in July. They will also be included in both the mobile app and the National Meeting Final Program.

SPECIAL TOPIC LECTURES


Buzzed Dancing: Honey Bees as Bioindicators of Habitat Quality
11:00 AM - 12:00 PM/Room: Ballroom III
Speaker: Maggie Couvillon
Moderator: Jennifer L Asher
Facilitator: TBN

The recent pollinator crisis exemplifies how public interest in scientific issues can be a mixed blessing, simultaneously raising awareness of pollinator decline, while generating rallying cries for untested solutions. Lack of forage is a factor contributing to bee declines. This stressor can act directly, where bees are unable to meet nutritional needs, or indirectly, where nutritional stress reduces the bees’ ability to cope with stressors like diseases and pesticides. Coverage has been wide: everyone wants to feed hungry bees. Such help is offered with best intentions, but efficacy is undermined by two crucial knowledge gaps: first, we do not know when and where bees lack forage. Providing flowers indiscriminately is common practice because current methods of surveying and cataloging floral abundance at landscape-scale are intensely time-consuming. Second, nutritional stress is often studied either in honey bees (Apis mellifera spp.) or non-honey bees, creating a dichotomy that limits the usefulness of results. There is a critical need to develop new methods to survey Apis forage on a landscape scale and to determine if non-Apis bees also prefer these areas. Without these data, it is not possible to implement a best management strategy for improving availability of forage that would benefit overall pollinator health. Here we explore how waggle dance, a behavior in which a honey bee forager communicates to her nestmates the vector from the hive to an important resource, usually food, may also be a powerful tool for ecology. Because honey bees perform dances only for the most profitable resources, these data provide spatial information about the availability of good quality forage for any given time. We argue that waggle dance decoding may inform on a range of ecological, conservation, and land management issues. Thus, one species and methodology gives a novel measure of a landscape's profitability that may be relevant not just for honey bees, but also for other flower-visiting insects. The audience will learn the background on the honeybee waggle dance; how we know what we know with the waggle dance and using waggle dances in research; and what we can still find out, the current state of the field, and future directions. The target audience is anyone with a minimum science background, but expertise in bee behavior is not necessary.

This Special Topic Lecture is sponsored in part by American College of Lab Animal Medicine/American Society of Laboratory Animal Practitioners Program Committee (ACLAM/ASLAP).

Charles C Hunter Lecture: "Lions, Tigers and Bears, Oh My!"

11:00 AM - 12:00 PM/Room: Ballroom I
Speaker: Cindy P Driscoll
Moderator: Leah J Schmidt
Facilitator: TBN

Lions, tigers, and bears, indeed! Just add fish, deer, birds, whales, snakes, and bats and you'll what it is like to be a wildlife veterinarian. Why would anyone want to be in the frozen mountains in winter and the steamy Chesapeake Bay Islands in heat of summer? To be outside, working with a wide variety of Maryland species, the great Maryland Department of National Resources biologists, and fellow veterinarians from all around the world is the best job anyone could experience. The speaker has taught wildlife diseases at the University of Maryland and also teaches aquatics in veterinary medicine via short courses. This lecture could be of interest to anyone attending the meeting, including technicians, researchers, and veterinarians.

This Special Topic Lecture is sponsored in part by Committee for Technician Awareness and Development (CTAD).

Lessons and Insights through the Story of Elizabeth R Griffin

11:00 AM - 12:00 PM/Room: Ballroom II
Speaker: Caryl Griffin Russell
Moderator: Jason S Villano
Facilitator: TBN

The Occupational Safety and Health Act of 1970 was promulgated to protect employees from hazards in the workplace. The Guide for the Care and Use of Animals also emphasizes that an animal research institution must establish an occupational health and safety program (OHSP). In 1997, a young woman named Elizabeth R. Griffin, contracted Macacine herpesvirus 1 while working with rhesus macaques. Her incident and eventual death highlighted vulnerable areas in OHSPs, including practices which potentially impacted work safety and effective emergency response to hazard exposures. In this talk, Caryl Griffin, mother of Beth and founder of the Elizabeth R. Griffin Foundation, will share Beth’s story and how it impacted laboratory animal science, especially as it pertains to biosafety/biosecurity policies and practices. The audience will hear Beth’s story and how this can provide a springboard for reviewing current safety practices integral to an animal care and use program. Applying lessons learned and putting ideas into action to address safety will also be reviewed as cornerstones to build a culture of care and responsibility in laboratory animal science and research. This lecture is appropriate for all attendees, including individuals from the animal care and use program management, veterinarians, IACUC members, compliance and biosafety officers, animal care staff, and researchers. This lecture is sponsored by the Georgetown University Center for Global Health Science and Security, and the Association of Primate Veterinarians.

This Special Topic Lecture is sponsored in part by Georgetown University Center for Global Health Science and Security and the Association of Primate Veterinarians (APV).

Listening to Your Inner Goddess: A Spontaneous SCID Pig as an Emerging Model for Cancer and Regenerative Medicine Research

11:00 AM - 12:00 PM/Room: Ballroom IV
Speaker: Christopher K Tuggle
Moderator: Jodi A Scholz
Facilitator: Nicholas J Rindels

Severe combined immune deficient (SCID) mice have been used for many years in xenograft research because the lack of an adaptive immune system permits the growth and subsequent study of human cells in an in vivo environment. However, rodents are an imperfect model for several aspects of human biology and applied medical research. On the other hand, the domestic pig has anatomical, physiological, and genomic similarities to humans that provide significant value as an alternative to rodent models. Further, SCID pigs have been reported, including the spontaneous SCID pig at Iowa State University (ISU). This special topic lecture will describe the serendipitous discovery and characterization of the ISU SCID pig, which has been shown to contain mutations in the Artemis gene, named for the Greek goddess of the hunt, childbirth, and the protector of small children. Artemis is required for normal DNA repair, including somatic recombination necessary for B and T lymphocyte production, and thus Artemis mutations cause this severe immunodeficiency. The presentation will also cover new research studies and husbandry protocols for maintaining these highly disease-susceptible animals in strict biocontainment. These methods have been used to successfully maintain specific pathogen-free SCID pigs for up to 6 months (>100 kg). The ISU SCID pig has been successfully used to study both zoonotic pathogens as well as those that cannot be propagated in rodents, grow several types of human cancers, and study engraftment of human skin. These studies and accompanying animal protocols have established SCID pigs as a valuable large animal xenograft model.

MONDAY AFTERNOON

PANEL DISCUSSIONS


An Outdoor Play Area for Laboratory Beagles—A Whole New Level of Enrichment!
12:30 PM - 2:00 PM/Room: 337
Leaders/Panelist: Carolyn M Allen, Brian J Ebert, Chris L Medina
Moderator: TBN
Facilitator: TBN

AbbVie maintains a sizeable population of chronically housed beagles, many of which reach retirement age around ~4.25 years, which then become candidates for our adoption program. In early 2017, we began having casual conversations around the possibility of creating an outdoor exercise/play area for our dogs. Casual conversations quickly turned into regularly scheduled meetings and the official planning began. Since dedicated outdoor canine play areas are not common practice in the pharmaceutical industry, we anticipated some resistance. We felt moving forward with this idea not only served in the best interest of our dogs and animal welfare, but could have some benefit to both our staff and overall transparency for the company. The proposal was drafted and presented to upper management and we received immediate support. In rapid fashion, the outdoor area was completed and ready for use in late 2017. Many meetings were held and a multitude of questions were asked before and during the project, with the process being closely monitored by key personnel from facilities, veterinary and behavioral staff, and our animal welfare group. This panel will be compromised of these key personnel involved in the planning, decision making, and implementation of our newly christened outdoor play area.

Optimizing Rodent Survival Surgery Outcomes

12:30 PM - 2:00 PM/Room: 339
Leader: Allison Williams, Kimberly Y Jen
Moderator: Allison Williams
Facilitator: TBN
Panelist: Melissa C Dyson, Velu Karicheti, Steven C Kreuser, Rachel Rubino

Successful surgery requires careful, detailed planning; skilled, attentive personnel; and appropriate facilities and equipment. The objective of this panel is to share varied approaches to optimize surgical outcomes in rodents. The content is suitable for rodent surgery novices, experienced rodent surgeons desiring a review, and program directors wishing to improve the success of their surgical program. The panel will feature brief presentations describing how each organization implements vital components of a rodent surgical program with successful outcomes. Program participants will include experienced professionals from a contract research organization, a pharmaceutical company, a nonprofit organization, and academia. Panel discussion will include the development and implementation of a comprehensive training program, including systems to ensure personnel are competent and proficient. Methods to maintain certification levels will also be shared. Gentle tissue handling and firm understanding of basic anatomy, physiology of wound healing, strict adherence to aseptic principles, and attentive postprocedural care are all key to ensuring successful surgical outcomes, optimal animal welfare, and ultimately, good science. Training and effective approaches for common models, including catheterized and non-catheterized models, will be discussed. Panelists will share how the following topics are accomplished at their respective institutions: 1) development and implementation of a comprehensive training program; 2) procedures for pre- and post-operative care; and 3) best practices for aseptic rodent surgery. Finally, the session will conclude with an interactive session on surgical complications, encouraging participation with audience members. Case scenarios will be presented and volunteers from the audience will be given an opportunity to troubleshoot the challenges presented. The panelists will offer insight into the discussions as all work to identify the root cause, as well as present potential corrective actions. The attendees will be encouraged to share experiences and/or practices observed at their home institutions.

Pathology Quiz Bowl

12:30 PM - 2:00 PM/Room: 341
Leader: Cindy L Besch-Williford
Moderator: Craig L Franklin
Facilitator: TBN
Panelist: Cindy L Besch-Williford, Angela K Brice, Craig L Franklin

This panel discussion will consist of an informal review of the pathology of laboratory animals in the form of an image-based quiz. Topics will include lesions of well-described infectious and noninfectious diseases, pathological manifestations of emerging diseases, and selected phenotypic characteristics of important genetically engineered animal models. The images will be educational and challenging to laboratory animal specialists at all levels of pathology expertise. Targeted audience is comparative medicine trainees, laboratory animal veterinarians, pathologists, and scientists. Participants from comparative medicine training programs have the opportunity to receive a fabulous cash prize for the highest score. A participation cash prize is also provided. The comparative medicine trainee with the highest score will be recognized at the Committee for Laboratory Animal Training and Research (CLATR) luncheon on Tuesday. Participants will learn gross and histologic pathology of laboratory animals.

This Panel Discussion is sponsored in part by CLATR and IDEXX BioResearch.

Sharing Our Message: Tips and Tools for Reaching Out

12:30 PM - 2:00 PM/Room: 343
Leader: Emily C Slocum
Moderator: Pamela A Straeter
Facilitator: Sarah J Gilliam
Panelist: Keely McGrew, Julie E Roller, Emily C Slocum, Terri A Swanson

Whether your outreach is formal or informal, we hope to give you the tips and tools to help with getting your message out there. Content will range from targeted presentations to success stories. Our discussion will give you the connections and resources you need to be successful in your own outreach efforts. The panel will discuss Public Outreach: The Why and How; The Importance of Education: The UT Southwestern Medical Center Outreach Team, as well as the Pfizer Drug Discovery Game, both of which are used in outreach efforts for everyone from kids to Congress. This session will also explain the importance of putting animal research into the context for public and Celebrate the Mouse: What's Happening In Research Outreach Program opportunities. This panel discussion targets anyone in our field interested in public outreach.

This Panel Discussion is sponsored in part by AALAS Foundation.

WORKSHOPS


W-05 Essentials of IACUC Administration (EIA) (8-hour workshop continued Tuesday 8:00 AM)
1:00 PM - 5:00 PM/Room: 348
Leader/Faculty: Elaine K Kim, Stacy L Pritt, Trina Smith
Facilitator: Ashley Savannah
Workshop Fee: $250 Workshop Limit: 50

This workshop will provide attendees with knowledge and tools to effectively manage an animal care and use program through informational presentations, as well as opportunities to engage in small-group activities using active learning methodologies; troubleshoot real-life examples; and debate topics such as reduction of administrative burden. This course covers approximately 8 hours in two sessions. The participants will be able to 1) list key components of an IACUC program; 2) understand the responsibilities of IACUC administrators; 3) discuss strategies for creating a culture of research and teaching success; 4) operationalize policy and regulations; and 5) implement best practices to ensure that all animal care and use program personnel have the support they need to strengthen the IACUC and the animal care and use program. The target audience comprises experienced IACUC administrators and support staff, as well as training and compliance personnel who are familiar with basic IACUC functions. Participants should plan to attend both workshop sessions. Part 1 features an IACUC administration overview; information on managing submissions; semiannual activities; small group activities; and a current topics discussion. Part 2 features training and occupational health; post-approval monitoring; allegations and noncompliance; small group activities; current topics discussion; and a question and answer session.

This Workshop is sponsored in part by Public Responsibility in Medicine and Research (PRIM&R).

W-06 How to Deal with Anesthetic Complications

1:00 PM - 5:00 PM/Room: 345
Leader: Cholawat Pacharinsak
Faculty: Cholawat Pacharinsak, Samuel W Baker
Facilitator: TBD
Workshop Fee: $140 Workshop Limit: 25

In this advanced workshop, attendees will learn to recognize and troubleshoot anesthetic complications. To increase anesthetic safety, continuous monitoring is essential to identify these complications. Anesthetists must know how to interpret these monitoring parameters and identify the causes of these complications to respond appropriately. The workshop will cover the general anesthetic periods of premedication, induction, maintenance, and recovery for large animal species. Although a large animal workshop, questions from other species are encouraged. It’s not mandatory to previously take a basic anesthetic monitoring workshop, but it is highly recommended. This workshop is suited for veterinarians, veterinary technicians, IACUC members, and researchers.

This Workshop is sponsored in part by Kent Scientific and VetEquip Inc.

W-07 Managing the Gap: Working and Leading in Multigenerational Teams

1:00 PM - 5:00 PM/Room: 349
Leader/Faculty: Jamie Mueller
Facilitator: Temeri Wilder-Kofie
Workshop Fee: $140 Workshop Limit: 50

This workshop will increase your awareness and understanding in managing and reducing generational gaps to improve your work and leadership across generational cultures, including a focus on working with millennials. Participants will increase their overall generational awareness and understanding of issues, such as why millennials work differently than previous generations. Participants will also develop effective strategies for communicating across generations, learn how to adapt style in generationally diverse situations, learn the skills necessary to do so for organizational and team effectiveness, and learn strategies to resolve conflict and build trust and sustainable relationships across generations. The workshop is targeted to directors and managers who manage team members from different generations and team members who work and collaborate with a variety of different generations.

W-03B Microsurgery Skills Training Using Surgical Loupes (offered twice, also Monday 8:00 AM)

1:00 PM - 5:00 PM/Room: 347
Leader: Robert F Hoyt Jr
Faculty: Tannia S Clark, Randall R Clevenger, Tanya L Herzog, Kenneth R Jeffries, Karen J Keeran, Elena Kuznetsova, Audrey Noguchi, Gayle Z Nugent, Tom L Thomas
Facilitator: Jennifer L Asher
Workshop Fee: $250 Workshop Limit: 20
See Monday AM for description.

This Workshop is sponsored in part by Midwest Veterinary Supply, Q-Optics Surgical Loupes, SurgiReal Products Inc, Supramid Suture and RICA Surgical Products.

W-08 Teaching Monkeys to Cooperate with Restraint: Using Positive Reinforcement Training and Temperament Testing Methods (8-hour workshop continued Tuesday 8:00 AM)

1:00 PM - 5:00 PM/Room: 346
Leader: Jaine E Perlman
Faculty: Mollie A Bloomsmith, Kristine Coleman, Jennifer L McMillan
Facilitator: Mark J Prescott
Workshop Fee: $250 Workshop Limit: 50

The workshop includes 8 hours of instruction on using positive reinforcement training (PRT) to teach monkeys to cooperate with various restraint procedures, as well as provide information about using temperament testing to assist in selection of subjects and planning for their training. Participants will learn approaches to training laboratory primates to cooperate with restraint for sample collection (e.g., blood), administration (e.g., injections), and chair restraint. RT is an important refinement in the care of nonhuman primates and an effective means of improving their welfare. However, animals respond differently to restraint and measuring temperament provides insight into how individuals might respond to these procedures, allowing for individualized and more effective training plans. The goals are to 1) introduce participants to animal training terminology and techniques; 2) teach PRT techniques as they apply to restraint procedures, such as the use of the cage squeeze back mechanism and chair restraint; and 3) teach methods to assess and quantify temperament in monkeys and to use this information to develop individualized training plans. Participants will learn how to establish a strong foundation for successful restraint training using PRT techniques, and how to incorporate alternative techniques such as negative reinforcement to meet research timelines. They will learn to identify monkeys who are engaged in the training process and how to increase the involvement of monkeys who seem uninterested in training. Participants will learn how to shape behavior and apply desensitization techniques, how to maintain trained behaviors over time, and how to transfer trained behaviors among multiple staff members. Participants will learn how temperament can impact training approaches and the anticipated timelines for training to cooperate with restraint. Understanding the intersection of individual differences in temperament and animal training will aid in the design of more efficient animal training programs. This workshop is designed for those experienced in working with primates, including behavior specialists, animal caregivers, research technicians, animal managers, veterinarians, and investigators.

This Workshop is sponsored in part by NC3Rs, Lomir Biomedical Inc, Carter 2 Systems and HYBEX Innovations Inc.

W-09 Would You Like to Improve Your Suturing and Rodent Surgery Aseptic Technique?

1:00 PM - 5:00 PM/Room: 350
Leader: Marcel I Perret-Gentil
Faculty: Szczepan Baran, Luke Brinkman, Marcel Perret-Gentil, Miguel Torres
Facilitator: Rebecca A LaFleur
Workshop Fee: $140 Workshop Limit: 30

You may feel proficient, even confident, in performing rodent surgery. However, you may be surprised how small improvements can have a huge impact on your animal’s recovery and data. Participants will learn and refine commonly used suture and knot-tying techniques. The workshop will focus on appropriate hand-eye coordination to improve suturing skills. A state-of-the-art inanimate model will be introduced and used during the suture practice. Additionally, easy to apply hands-on exercises will be put into practice that have been shown to significantly improve aseptic technique. Common errors and complications will be discussed and addressed. This workshop is designed for individuals who have minimal or no suturing skills, but is also a great opportunity for those with considerable experience wanting to upgrade their skills and teach others enhanced technique. Target audience includes veterinarians, trainers, research staff, veterinary technicians, and others.

This Workshop is sponsored in part by Kent Scientific, Atramat, and SurgiReal Products Inc.

PLATFORM SESSIONS

2:15 PM-5:00 PM

Platform Session abstracts will be available on www.aalas.org in July. They will also be included in both the mobile app and the National Meeting Final Program.

SEMINARS


An Infiltrator in the Lab: Why Do Some Accusations of Animal Cruelty Make Headlines While Others Avoid Media Attention?
2:45 PM - 5:00 PM/Room: Ballroom I
Leader: Wendy Jarrett, Kirk Leech
Moderator: Ana I Santos
Facilitator: TBN

Animal rights activists have long used the tactics of undercover filming and exaggerated claims to accuse animal researchers of malpractice. Prescreening and other security measures can help to stop an infiltrator gaining access to the lab, but these measures do not always work. In this seminar, we will explore the strategies that you and your colleagues can employ to make sure that an infiltration scenario or accusation scenario does not cause your institution lasting reputational damage. By studying past examples of infiltrations and accusations in the UK and Europe, the steps taken by the organizations involved, the media coverage that followed them, and the results of official investigations into the claims made, we will help participants to understand what makes a successful media and communications response. Participants will also learn how to prepare robust mechanisms in advance of potential crisis situations and how openness and proactive communications can help to lessen the chances of negative publicity. The target audience for this seminar is animal care staff, facility managers, researchers, and those with a communications role.

Speakers/Topics:

2:45 Ana I SantosWelcome and Introduction
2:50 Wendy JarrettWhat Is a Crisis?
3:10 Kirk LeechUncover Filming and Accusations—How Should Institutions Respond?
3:40 Wendy JarrettHow Communication Helps Prevent Negative Publicity
4:10 Kirk LeechExamples of Openness Across the EU
4:30 Ana I SantosQuestions and Answers

Back to the Basics: Practical Biomethodology for Miniature Swine Users

2:45 PM - 5:00 PM/Room: Ballroom II
Leader: Derek Brocksmith
Moderator: Ian Stewart
Facilitator: Vikki Wehmeier

Miniature swine presence in biomedical research continues to expand and gain traction. Practical biomethodology is a commonly requested topic by researchers. Biomethodology, including best practices for surgical modeling, behavioral modification, stress minimization, and care during life stages, will be highlighted in this seminar. Miniature swine applications in toxicology, pharmacology, and training resources will be other areas of emphasis. We expect a broad audience will benefit from these presentations, including laboratory animal veterinarians, attending veterinarians, veterinary and animal technicians, facility managers, graduate students, and scientists interested in miniswine model research and use.

Speakers/Topics:

2:45 Derek BrocksmithWelcome and Introductions
2:55 Guy BouchardStress-Free Blood Collection and Common Vascular Access
3:20 Michael SwindleSurgery, Anesthesia, and Common Peri/Postoperative Complications
3:45 Paul ShermanMiniature Swine as a Model for Human Brain Development
4:10 Derek Brocksmith

Grade School Training: Behavior Enhancement to Improve Animal Handling and Welfare

4:30 Alain Stricker-Krongrad Miniature Swine Lineages for Toxicology and Pharmacology

This Seminar is sponsored in part by Sinclair BioResources, LLC.

Integrated Strategies to Enhance the Welfare of Primates in Research
2:45 PM - 5:00 PM/Room: Ballroom III
Leader/Moderator: Ghislaine Poirier
Facilitator: Margaret S McTighe

Despite growing efforts to develop nonanimal alternative research methods, nonhuman primates (NHP) remain critical species for increasing our understanding of biological mechanisms and for the development of new medicines. Because they have not evolved as domesticated species, and because of their complex social structure and communication characteristics, NHPs require special attention to help them adapt and maintain good health and welfare whilst in our care, at all stages of their lives. New strategies and methods are continuously being developed and trialed in various settings, from the time NHPs are bred to the time they are used in experimental studies, to refine practices and help enhance their welfare. Sharing experiences and disseminating practices that are associated with welfare benefits and how to measure them are key to accelerate progress. The seminar will offer opportunities to share novel approaches for NHP housing and care from the perspective of animal breeding, the research setting, and a 3Rs organization; learn and discuss behavioral program managements in the country of origin and on arrival at a research establishment to facilitate acclimation to the environment and procedures; discuss the development and implementation of NHP performance-based standards across organizations; and learn about housing designs that respond to NHP behavioral needs and the needs of research. Animal technicians, study technicians, veterinarians, facility managers and supervisors, animal welfare officers, IACUC members, breeders, and animal research organizations will benefit from this seminar.

Speakers/Topics:

2:45 Ghislaine PoirierWelcome and Introduction
2:55 Sandra R LefinA Successful Behavior Management Strategy in the Breeder's Country of Origin to Prepare Macaques for Laboratory Conditions
3:25 Ghislaine PoirierHolistic Approach to Facilitate NHP Acclimation at a CRO
3:55 Gina WilkersonIndustry Collaborations to Implement Performance Based Housing Standards with CRO Partners
4:25 Mark J PrescottSupporting the NHP Research Community to Improve Animal Welfare and Scientific Outcomes


Rat Tickling: A Technique for Improving Rat Welfare
Monday, October 29, 2:45 PM - 5:00 PM/Room: Ballroom IV
Leader: Megan R LaFollette
Moderator: Brianna N Gaskill
Facilitator: TBN

Rats initially fear handling by laboratory personnel, which can lead to several negative effects such as increased stress, decreased welfare, and resistance to handling. These outcomes can be mitigated by using rat tickling, a human-animal interaction technique that mimics aspects of rat rough-and-tumble play. Rat tickling can result in positive outcomes, such as increased positive affect, improved handling procedures, and social enrichment. Participants will learn the background of the development of rat tickling, how and why to implement it, its minimum effective dosage, and barriers to its implementation. The target audience for this presentation is research staff, animal care staff, veterinarians, and vivarium managers who work with rats.

Speakers/Topics:

2:45 Megan LaFolletteWelcome and Introductions
2:55 Brianna N GaskillIntroduction to Rat Tickling: A Systematic Review
3:25 Sylvie CloutierApplications of Rat Tickling: Injections and Blood Sampling
3:55 Melissa P SwanRat Tickling and Experimental Effects: Cage Color
4:20 Megan LaFolletteRat Tickling Implementation: Dosage and Survey