WEB-040A: The impact, susceptibility, and prevalence of viral infections of rats have the potential to rise as a result of the greater production of the greater production of genetically engineered rats, for example with CRISPR technology. Greater infection risks may occur from genetic changes themselves or by globally sharing unique rats from noncommercial sources. Among known viral infections of rats, serological surveys indicate that parvoviruses, coronaviruses, cardioviruses, and pneumoviruses are the most prevalent in laboratory colonies. A new polyomavirus and a new cardiovirus that cause disease in laboratory rats have been reported. Furthermore, advances in genomics have enabled screening for previously unknown viral infections. Recent metagenomic analyses of feces or intestinal contents of wild rats detected previously unknown viruses that could potentially cause infections in laboratory rats. This webinar will provide an update on longstanding as well as newly recognized viral infections of rats.
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