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Gut Microbiota: Variability and Translatability in Rodent Models
March 18, 2020
12:00 PM - 1:30 PM CT

WEB-060: The gut microbiota (GM) is the collection of commensal microorganisms that occupy the intestinal tracts of animal species.  In the past few decades, technologies to define and analyze these complex communities have advanced greatly and are now readily available and cost-effective.  Of importance to the biomedical research community is the growing wealth of data showing marked variation of GM among contemporary rodent colonies and the many environmental factors that can influence GM composition.  More importantly, such differences have been associated with changes in model phenotypes ranging from models of intestinal to neurologic disease.  This has resulted in concerns about the role of GM in model reproducibility.  While in some cases, individual species of bacteria, such as segmented filamentous bacteria or species of Helicobacter, have been implicated in phenotype changes, current challenges center on how complex interactions among bacterial communities can influence model phenotypes and reproducibility.  Moreover, the translatability of laboratory rodent GM has recently been scrutinized.  To this end, pet store and wild mice, which are exposed to more antigen-laden environments when compared to their laboratory counterparts, are colonized by GMs that contribute to more translatable immune system development. The latter can lead to marked differences in disease model phenotypes. This webinar will summarize our current understanding of the role of GM in model reproducibility and translatability as well as the many challenges now confronting the laboratory animal community.

Audience: veterinarians, veterinary technicians, animal health technicians, research staff involved with rabbit surgical models.

The fee is per connection: One connection can be used for site or group training. If multiple connections are needed, please place and order per connection. Discounts are available by using the Store Order Form PDF when you purchase 5 or more connections. The 1.5 hour time frame will allow for plenty of time to submit your questions, thus giving you a more personalized training experience. Time and date not convenient for you? Share the presentation recording afterward with your staff. AALAS will provide the link to view the webinar recording to all registrants several days after the webinar concludes. Within 1 to 3 business days after ordering the webinar, you will be sent an email with a link to register and view the webinar on the GoToWebinar website.

AALAS CEUs: You can apply for up to 1.5 CEUs for the Technician Certification Registry or CMAR recertification. Please use the forms on the AALAS website or online CEU submission.

RACE CEs: This program 37-39793 is approved by the AAVSB RACE to offer a total of 1.00 CE Credit (1.00 max) being available to any one veterinarian: and/or 1.00 Veterinary Technician CE Credits (1.00 max). This RACE approval is for the subject matter category of Medical Program. This approval is valid in jurisdictions which recognize AAVSB RACE; however, participants are responsible for ascertaining each board's CE requirements. RACE does not "accredit" or "endorse" or "certify" any program or person, nor does RACE approval validate the content of the program.

  • List Price: $175.00
  • Member Price: $115.00
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Presenter: Craig Franklin, DVM, PhD, DACLAM

Dr. Franklin attended the University of Missouri (MU), where he received his DVM and PhD.  He is currently a Professor of Veterinary Pathobiology at MU and directs the Mutant Mouse Resource and Research Center, a member of a 4-institution, NIH-funded...

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